We have a lot of catching up to do.
|—||From Seth Godin’s the dip.|
A Moveable Yeast: modeling shows proteins never sit still
Our body’s proteins – encoded by DNA to do the hard work of building and operating our bodies – are forever on the move. Literally, according to new findings reported by Trey Ideker, PhD, chief of the Division of Genetics in the UC San Diego School of Medicine, and colleagues in a recent issue of the Proceedings of the National Academy of Sciences.
Hemoglobin protein molecules, for example, continuously transit through our blood vessels while other proteins you’ve never heard of bustle about inside cells as they grow, develop, respond to stimuli and succumb to disease.
To better understand the role of proteins in biological systems, Ideker and colleagues developed a computer model that can predict a protein’s intracellular wanderings in response to a variety of stress conditions.
To date, the model has been used to predict the effects of 18 different DNA-damaging stress conditions on the sub-cellular locations and molecular functions of more than 5,800 proteins produced by yeasts. They found, for example, that yeast proteins could move from mitochondria to the cell nucleus and from the endoplasmic reticulum to Golgi apparatus.
Though the model debut involved yeasts, researchers said the coding can be adapted to study changes in protein locations for any biological system in which gene expression sequences have been identified, including stem cell differentiation and drug response in humans.
Image courtesy of Material Mavens
LLTG: Librarians Love Tim Gunn
And so begins the movement to reclaim the word ‘schoolmarm.’
ALL OF MY FAVORITE THINGS
I guess we could call ourselves schoolmarm then :)
i know, i know!
The best quiz ever!
For the 50th anniversary of A Hard Day’s Night by The Beatles,eviews the DVD release:
"In the unmistakable alchemy of their sound – and in their authentic laughter as they run from shrieking fans during the film’s opening credits – The Beatles embodied the hope and vitality the world was looking for then and still loves to this day. Like Louis Armstrong, they created music that, even when sad, is bursting with joy. All those hard days and nights paid off, for more than any band I can think of, they captured the yeah-yeah-yeah of happiness."
Read the full review: 'A Hard Day's Night': A Pop Artifact That Still Crackles With Energy
Photo via Janus films
On Saturday, July 26, the 2014 Empowering through Beauty (ETB) Expo, “A Celebration of Beauty,” will be held at the Stamford Innovation Center. The expo will feature the EmpowerHER awards …
Amazon officially unveiled an all-you-can-read subscription service on Friday that gives you access to more e-books than you could ever finish. That’s right, never have more books been available to you — unless you have a public library card. …
get all the books (dvds, cds, audiobooks) you want (and maybe did not know you wanted) for free at the Ferguson Library. You can even attend our events without paying a dime.